Aidan D. Meade BSc MSc PhD MInstP

Brief Biography

BSc in Experimental Physics from University College Dublin in 1997. MSc in Physical Sciences in Medicine from Trinity College Dublin, 2000. PhD in Physics from Dublin Institute of Techology, 2010 with a thesis entitled "Spectroscopic and chemometric approaches to radiobiological analysis". Member of the Institute of Physics, the Radiation Research Society (US), the Association of Radiation Research (UK), and the International Society for Clinical Spectroscopy (CLIRSPEC). Previously employed as a Medical Physicist in the Department of Medical Physics and Bioengineering at St. James's Hospital (1997 to 2002). Joined staff of School of Physics, DIT in December 2002.

Teaching Interests

General Medical Physics and Clinical Measurement. Radiation Protection and Radiobiology. Non-Ionising Radiation. Nuclear and Particle Physics.

Research Interests

Radiobiology. Biophotonics. Multivariate modelling and data mining techniques. On secondment from September 2008 to September 2010 as Project Coordinator under the HEA PRTLI Cycle 4 funded National Biophotonics and Imaging Platform at the Focas Institute.

Publications

See Google Scholar profile for a full list of publications

Refereed Proceedings Abstracts

  1. Evaluation of T-cell activation with Raman micro spectroscopy, N. Chaudhary, A.D. Meade, Workshop FT-IR Spectroscopy in Microbiological and Medical Diagnostics, Robert Koch Institute, Berlin, 2017.
  2. Optimization of classification of breast cancer antigenicity with fast-FTIR imaging, Sebastian Nagorski, Naomi Jackson, and Aidan D. Meade, Photonics Ireland 2017, NUI Galway.
  3. A prognostic assay of therapeutic treatment outcome using vibrational spectroscopy, Aidan Meade, Adrian Maguire, Sebastian Nagorski, Naomi Jackson, Niamh Lynam- Lennon, John V. Reynolds, Jacintha O'Sullivan, William Gallagher, Karin Jirstrom, Fiona Lyng, CLIRCON 2017, University of Manchester.
  4. Raman spectroscopy for identification of prostate cancer patients at risk of late radiation toxicity following radiotherapy, Daniel Cullen, Adrian Maguire, Jane Bryant, Mary Dunne, Marie Finn, John Armstrong, Orla Howe, Aidan Meade, Fiona Lyng, CLIRCON 2017, University of Manchester.
  5. Measurement of T-cell activation with Raman microspectroscopy, Neha Chaudhary, Adrian Maguire, Jane Bryant, Gráinne Kearns, Caroline Jefferies, Aidan D. Meade, CLIRCON 2017, University of Manchester.
  6. Spectroscopic detection of classic AT-radiosensitivity in-vitro, Adrian Maguire, Jane Bryant, Lisa White, Orla Howe, Fiona Lyng, Aidan Meade, CLIRCON 2017, University of Manchester.
  7. Investigation of the effect of chemical deparaffinisation approaches on vibrational spectra of tissue and their relationship to immunohistochemical antigenicity, Naomi Jackson, Adrian Maguire, Helen Lambkin, Aidan Meade, CLIRCON 2017, University of Manchester.
  8. Development of a high throughput (HT) Raman spectroscopy method for rapid screening of liquid blood plasma from prostate cancer patients, Medipally, D., Maguire A, J. Bryant, V. Unterreiner, J. Armstrong, M. Dunne, Lyng FM, Meade AD, SPEC 2016, Montreal.
  9. Use of Raman spectroscopy for the identification of mild, moderate and severe oral dysplasia and squamous cell carcinoma, Ibrahim O, Maguire A, Meade AD, Flint S, Byrne HJ, Lyng FM, Advanced Vibrational Spectroscopy for Biomedical Applications, SPEC 2016, Montreal.
  10. Optimisation of clustering methods in Raman and FTIR spectral imaging for applications in histopathology, A. Maguire, N. Jackson, N.Lynam-Lennon, J.V. Reynolds, J. O’Sullivan, and A.D. Meade, Microscopical Society of Ireland Annual Scientific Meeting, DIT, 2016.
  11. Measurement of T-cell activation with Raman microspectroscopy, N. Chaudhary, A. Maguire, J. Bryant, G. Kearns, C. Jefferies and A. D. Meade, Microscopical Society of Ireland Annual Scientific Meeting, DIT, 2016.
  12. Raman and FTIR spectroscopy for detection and diagnosis of prostate cancer using blood lymphocytes, Medipally, D., Maguire A, J. Bryant, V. Unterreiner, J. Armstrong, M. Dunne, Lyng FM, Meade AD, Advanced Vibrational Spectroscopy for Biomedical Applications, 21-23 March 2016, St. Catherine’s College Cambridge, UK.
  13. Optimisation of deparaffinizing and baking adherence techniques for breast tissue on calcium fluoride slides for FTIR and Raman imaging, N. Jackson, N. Chaudhary, H. Lambkin, A. Malkin, Meade AD, Advanced Vibrational Spectroscopy for Biomedical Applications, 21-23 March 2016, St. Catherine’s College Cambridge, UK.
  14. Investigation of Radiosensitivity in Fibroblasts and LCLs from Ataxia Telangiectasia Patients and Healthy Donors, L. White, J. Bryant, A. Maguire, A.D. Meade, P. Jeggo, M. Taylor, J. Hall, F. Lyng, O. Howe, Abstract 2-PS2D-12, International Congress on Radiation Research, Kyoto, Japan, 25-29 May 2015.
  15. Analyses of Ionising Radiation Effects In-Vitro and Ex-Vivo in Peripheral Blood Lymphocytes with Raman Spectroscopy, J. Bryant, A. Maguire, L. White, O. Howe, F. Lyng, A.D. Meade, Abstract 4-PS1B-52, International Congress on Radiation Research, Kyoto, Japan, 25-29 May 2015. 
  16. Comparison of Radiosensitivity Assays in AT Fibroblast Cell Lines and Healthy Donor Blood Samples, L. White, J. Bryant, A. Maguire, A.D. Meade, P. Jeggo, F. Lyng, O. Howe, European Radiation Research Society Annual Scientific Meeting, Rhodes, Greece, 14-19 September 2014. 
  17. Analyses of Ionising Radiation Effects In-Vitro and Ex-Vivo in Peripheral Blood Lymphocytes with Raman Spectroscopy, J. Bryant, A. Maguire, L. White, O. Howe, F. Lyng, A.D. Meade, European Radiation Research Society Annual Scientific Meeting, Rhodes, Greece, 14-19 September 2014.
  18. Radiosensitivity in Health Donors and ATM Deficient Fibroblast Cell Lines, L. White et al, Association for Radiation Research, Brighton, June 2014.
  19. The influence of DNA double strand break sensing via the ATM pathway on Raman spectra of lymphoblastoid cells, A. Maguire, I. Vega Carrascal, L. White, O. Howe, F. Lyng, A.D. Meade, European Radiation Research Society Annual Scientific Meeting, Dublin, September 2013. 
  20. The role of radiation type and dose for predicting G2 radiosensitivity in a cohort of donor blood, L.White, I. Vega Carrascal, A. Maguire, L. Sheilds, B. McClean, A.D. Meade, F. Lyng, O. Howe, European Radiation Research Society Annual Scientific Meeting, Dublin, September 2013. 
  21. Detection and analysis of radiobiological effects with vibrational spectroscopy and multivariate techniques, A.D. Meade and F.M. Lyng, Systems Radiation Biology, Oxford Brookes University, Oxford UK, September 2012.
  22. Investigation of carbon nanotube degradation in vitro and in vivo using Raman spectroscopy, J. Conroy, A.A. Shvedova, V.E. Kagan, A.D. Meade, A. Knyazev, D. Kelleher, Y. Volkov, Trinity College Dublin, IE, TechConnect World, Boston 2011
  23. Meade A.D., Byrne, H.J., Lyng, F.M., Analyses of radiobiological effect in-vitro and ex-vivo with vibrational spectroscopy, Irish Radiation Research Society Annual Scientific Meeting, Dublin, October 2010.
  24. Meade A.D., Byrne, H.J., Lyng, F.M., Analyses of radiobiological effect in-vitro and ex-vivo with vibrational spectroscopy, BioPic Biophotonics and Imaging Conference, Dunboyne Castle Hotel, October 2010.
  25. Meade A.D., Byrne, H.J., Lyng, F.M., Analyses of radiobiological effect in-vitro and ex-vivo with vibrational spectroscopy, European Radiological Research Annual Scientific Meeting, Stockholm, September 2010.
  26. Meade A.D., Broderick A., Lambkin, H., Muksinova K.N., Kirillova E.N., Revina V.S., Unterreiner V., Sockalingum G.D., Manfait M., Byrne, H.J., Lyng F.M., Detection of ionizing radiation damage in irradiated lung tissue using Fourier Transform Infrared microspectroscopy, Association for Radiation Research Annual Scientific Meeting, Oxford, June 2010.
  27. Meade A.D., Broderick A., Lambkin, H., Muksinova K.N., Kirillova E.N., Revina V.S., Unterreiner V., Sockalingum G.D., Manfait M., Byrne, H.J., Lyng F.M., Detection of ionizing radiation damage in irradiated lung tissue using Fourier Transform Infrared microspectroscopy, SPEC2010, Manchester, June 2010.
  28. Meade A.D., Clarke C., Knief P., Byrne, H.J., Lyng F.M., Selection of preprocessing methodology for multivariate regression of cellular FTIR and Raman spectra in radiobiological analyses, Irish Chemometrics Society Annual Scientific Meeting, University College Dublin, 16th April 2010.
  29. Nawaz, H, Meade, A.D., Lyng F.M., Byrne H.J., Raman spectroscopy for the evaluation of antincancer agents, Irish Institute for Metal Based Drugs Annual Scientific Meeting, DIT, 26th November 2009.
  30. Meade A.D., Byrne, H.J., Lyng, F.M., Spectroscopic and Chemometric Approaches to Radiobiological Analysis, Association for Radiation Research Annual Scientific Meeting, Glasgow, 2009.
  31. Raman spectroscopy – a platform for the rapid measurement of carbon nanotube-induced cytotoxicity, P. Knief, C. Clarke, E. Herzog, M. Davoren, F.M. Lyng, A.D. Meade, and H.J. Byrne, XLIV Zakopane School of Physics, International Symposium , “Breaking Frontiers: Submicron Structures in Physics and Biology”, 18th - 23rd May, 2009, Zakopane, Poland
  32. Meade A.D., Byrne, H.J., Lyng, F.M., Spectroscopic and Chemometric Approaches to Radiobiological Analysis, European Science Federation and European Molecular Biology Organisation Joint Syposium: “Spatiotemporal Radiation Biology – Transdisciplinary Approaches for Biomedical Applications”, St. Feliu de Guixols, Costa Brava, 2009.
  33. Meade A.D., Clarke, C., Bonnier, F., Poon, K., Garcia, A., Knief, P., Ostrowska, K., Salford, L., Nawaz, H., Lyng F.M., Byrne, H.J., Functional and Pathological analysis of biological systems using vibrational spectroscopy with chemometric and heuristic approaches, WHISPERS: First Workshop on Hyperspectral Imaging and Signal Processing: Evolution in Remote Sensing, Grenoble, 2009.
  34. Raman imaging for the investigation of the action of anti-cancer agents, Haq Nawaz, Franck Bonnier, Aidan Meade, Hugh J. Byrne, Fiona Lyng, SPEC 2008, Sao Jose dos Campos, Sao Paulo, Brazil, October 25-29, 2008.
  35. Spectroscopic imaging of Quantum Dot cellular interaction, Lorenzo Salford, Franck Bonnier, Aidan Meade, Hugh J. Byrne, Fiona Lyng, SPEC 2008, Sao Jose dos Campos, Sao Paulo, Brazil, October 25-29, 2008.
  36. Raman spectroscopy – a platform for the rapid measurement of carbon nanotube induced cytotoxicity, P. Knief, C. Clarke, E. Herzog, M. Davoren, F.M. Lyng, A.D. Meade, and H.J. Byrne, SPEC 2008, Sao Jose dos Campos, Sao Paulo, Brazil, October 25-29, 2008.
  37. Skin Characterisation by Infrared Spectroscopy, Syed Mehmood Ali, Aidan Meade, Franck Bonnier, Hugh J. Byrne, Fiona Lyng, SPEC 2008, Sao Jose dos Campos, Sao Paulo, Brazil, October 25-29, 2008.
  38. Biodosimetry and Biochemical Analyses of Radiobiological Response using Vibrational Spectroscopy, Meade A.D., Clarke C., Byrne, H.J., Lyng F.M., Annual Scientific Meeting of the Radiation Research Society, Massachusetts Convention Centre, Boston, USA, October 2008.
  39. Optical Vibrational Spectroscopy in the Analysis of Radiobiological Effects at the Cellular Level, Meade A.D., Sockalingum, G.D., Jeannesson, P., McClean, B, Manfait, M., Byrne, H.J., Lyng F.M., European Conference on the Spectroscopy of Biological Molecules, Bobigny, Paris, September 2007.
  40. Optical Analyses of Radiobiological Effects in Irradiated Cellular Systems, Meade A.D., Sockalingum, G.D., Jeannesson, P., McClean, B, Manfait, M., Byrne, H.J., Lyng F.M, International Congress of Radiation Research, San Francisco, July 2007.
  41. Optical Analyses of Radiobiological Effects in Irradiated Cellular Systems, Meade A.D., Byrne, H.J., Lyng F.M., RADAM COST P9 Conference, Royal College of Surgeons in Ireland, June 2007.
  42. Spectroscopic analyses of molecular radiobiological effects in biological systems, Meade A.D., Sockalingum, G.D., Jeannesson, P., Nguyen, T., McClean, B, Manfait, M., Byrne, H.J., Lyng F.M., Association of Radiation Research Annual Scientific Meeting, School of Pharmacy, Queen’s University Belfast, April 2007.
  43. Spectroscopic assays elucidate radiobiological effects at the molecular level in irradiated biological systems, A.D. Meade, F.M. Lyng, H.J. Byrne, Annual Scientific Meeting of the Radiation Research Society, Philadelphia Convention Centre, Philadelphia, USA, November 2006.
  44. Vibrational spectroscopy elucidates substrate-induced changes in proliferative capacity and viability in cultured keratinocytes, A.D. Meade, F.M. Lyng, H.J. Byrne, Microscopical Society of Ireland Annual Scientific Meeting, National University of Ireland, Galway, Ireland, August 2006.
  45. Growth substrate induced functional changes elucidated by FTIR and Raman spectroscopy in in-vitro cultured human keratinocytes, A.D. Meade, F.M. Lyng, H.J. Byrne, SPEC 2006 Shedding Light on Disease: Optical Diagnosis for the New Millennium, May 2006;
  46. Spectroscopic assays elucidate radiobiological effects at the molecular level in irradiated biological systems, A.D. Meade, H.J. Byrne, F.M. Lyng, SPEC 2006 Shedding Light on Disease: Optical Diagnosis for the New Millennium, Heidelberg, May 2006;
  47. Vibrational Spectroscopy and Radiobiological Assays of HaCaT Keratinocytes Post Exposure to Ionising Radiation, A.D. Meade, H.J. Byrne, F.M. Lyng, Radiation Research Society Annual Scientific Meeting, Denver, US, 2005;
  48. Raman and FTIR Spectroscopy demonstrates potential as a Novel Tool for Characterisation of Cellular Function Post-Ionising Radiation Exposure, A.D. Meade, H.J. Byrne, F.M. Lyng, Microscopical Society of Ireland Annual Scientific Meeting, DIT, 2005;
  49. Vibrational spectroscopy as a novel tool for the characterisation of cellular function post-ionising radiation exposure in HaCaT keratinocytes, A.D. Meade, H.J. Byrne, F.M. Lyng, European Radiation Research Society and Association of Radiation Research Joint Meeting, Leicester, 2005;
  50. Raman and FTIR Spectroscopy and Radiobiological Assays of HaCaT Keratinocytes Post Exposure to Ionising Radiation, A.D. Meade, H.J. Byrne, F.M. Lyng, European Young Investigator Conference, Gniezno, Poland, 2005;
  51. Correlation of spectroscopic and biochemical assays post-ionising radiation exposure in human skin cell analogues, A.D. Meade, H.J. Byrne, F.M. Lyng, SPIE Opto-Ireland, Dublin, 2005;
  52. Spectroscopic and Biochemical Evaluation of the Products of Ionising Radiation Exposure in Human Skin Cell Analogues, A.D. Meade, H.J. Byrne, F.M. Lyng, Proceedings of IACR Annual Scientific Meeting, Kilkenny, 2005;
  53. Raman spectral changes and radiobiological assays in human keratinocytes exposed to ionising radiation, A.D. Meade, H.J. Byrne, F.M. Lyng, Proceedings of APSM Annual Scientific Meeting, Galway, 2005;
  54. Electrical Safety Testing of Medical Radiological Installations, Meade A.D., Walsh C., Hegarty F., Dowling A., Kenny T., Gallagher A., Donohoe A., IPEM meeting - Commissioning of Diagnostic Radiology Installations, Royal Marsden Conference Centre, London, Nov 12th. 2002.
  55. Revised Risk Estimates for Energy Imparted from Latest A-bomb Survivor Data, A.D. Meade and J.F. Malone, Proceedings of the Annual Scientific Meeting of the Institute of Physicists and Engineers in Medicine, Durham 2002.
  56. Mammography Doses in Ireland, Gallagher, A., Dowling, A., Meade, A.D., Donohoe, A., Kenny, T., Malone, J.F., Proceedings of the Annual Scientific Meeting of the Institute of Physicists and Engineers in Medicine, Durham 2002.
  57. Evaluation of the Uncertainty in Risk Estimation for Low Level Ionizing Radiation, A.D. Meade and J.F. Malone, Proceedings of the European Congress of Medical Physics and Bioengineering, Belfast 2001, Physica Medica, 23(3).
  58. Patient Dose Survey of CT Examinations within Ireland, T. Kenny, A. Dowling, A Gallagher, A.D. Meade and J.F. Malone, Proceedings of the European Congress of Medical Physics and Bioengineering, Belfast 2001, Physica Medica, 23(3).
  59. Patient Dose Survey of Mammographic Examinations within Ireland, A Gallagher, A. Dowling, T. Kenny, M. Murphy, A.D. Meade and J.F. Malone, Proceedings of the European Congress of Medical Physics and Bioengineering, Belfast 2001, Physica Medica, 23(3).
  60. Development of a GMP Facility at the Irish Blood Transfusion Service, C. Walsh, A.D. Meade, J. Galligan, B.M. Mc Mahon, Proceedings of the Annual Scientific meeting of the Association of Physical Scientists in Medicine, Dublin, 2000.
  61. A review of Equipment Validation and Good Manufacturing Practice, C. Walsh, B.M. Mc Mahon, A.D. Meade, N. O'Hare, Proceedings of the Institute of Physics and Engineering in Medicine Annual Scientific Meeting, Southampton 2000.
  62. Measurement of Temperature in GMP Validation of Temperature Controlled Environments Equipment, C. Walsh, J. Galligan, A.D. Meade, P. Coakley, B.M. Mc Mahon, Proceedings of the British Blood Transfusion Society Annual Scientific Meeting, Nottingham 2000.
  63. Temperature Measurement Methods for GMP Validation of Blood Plasma Freezing Equipment, A.D. Meade, C. Walsh, A. Gallagher, J. Galligan, P. Coakley, B.M. Mc Mahon, Proceedings of the Institute of Physics and Engineering in Medicine Annual Scientific Meeting, Southampton 2000.
  64. Risk Estimation in Diagnostic Radiology, A.D. Meade, D.M. Marsh and J.F. Malone, Proceedings of the Annual Scientific meeting of the Association of Physical Scientists in Medicine, Galway, 1998.